Experimental infectious pancreatic necrosis infections: propagative or point-source epidemic?

Infectious Pancreatic Necrosis

Infectious pancreatic necrosis (IPN) is a viral infection primarily of trout and salmon, but the virus has also been isolated from a wide variety of other fish species. The infection is characteristically seen in trout as an acute disease causing high mortality in fry and fingerlings. However, it may also occur as a benign and inconspicuous infection (Bullock et al. 1976). Because high fish los...

DNA immunization and viral load in vaccinated trout following experimental infection with infectious pancreatic necrosis virus (IPNV)

Biophysical studies of infectious pancreatic necrosis virus.

The molecular weight of infectious pancreatic necrosis virus (IPNV) has been determined by analytical ultracentrifugation and dynamic light scattering. The sedimentation coefficient of the virus was found to be 435S. The average value for molecular weight is (55 +/- 7) x 106. The virus genome consists of two segments of double-stranded RNA (molecular weights, 2.5 x 106 and 2.3 x 106), which rep...

Infectious Pancreatic Necrosis Virus Causing Clinical and Subclinical Infections in Atlantic Salmon Have Different Genetic Fingerprints

Infectious pancreatic necrosis virus (IPNV) is the causative agent of IPN, an important disease of salmonids. IPNV infections result in either sub-clinical or overt disease and the basis of this difference is not well-understood. The objective of the present study was to determine the VP2 gene of the virus associated with the different forms of clinical manifestation. Groups of Atlantic salmon ...

Thermal inactivation of infectious hematopoietic necrosis and infectious pancreatic necrosis viruses.

A plaque assay was used to follow the inactivation kinetics of infectious hematopoietic necrosis virus and infectious pancreatic necrosis virus in cell culture media at various temperatures. Inactivation of infectious hematopoietic necrosis virus in a visceral organ slurry was compared with that in culture media.